Quinolines and derivatives
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Filtered Search Results
eMolecules 2-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | 70639-78-0 | MFCD11007961 | 1g
AstaTech | 2-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | 1g | 323612351 | K10089 | 95.000 | 70639-78-0 | MFCD11007961 | 189.170 | C10H7NO3
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eMolecules EMOLECULES INC
5000474165 METHYL 2-QUINOLIN-6-YLAC 10G
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eMolecules EMOLECULES INC
5000474041 METHYL 2-QUINOLIN-6-YL 250MG
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eMolecules EMOLECULES INC
5000474152 S-TETRAHYDROFURAN-3-AMINE 1G
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Medchemexpress LLC Methyl phenyl sulfone | 3112-85-4 | MFCD00014741 | 10g
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Methyl phenyl sulfone is a drug impurity
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eMolecules EMOLECULES INC
5000474213 METHYL 2-QUINOLIN-6-YLAC 25G
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Selleck Chemical LLC Chelerythrine-E0124-25MG
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Chelerythrine (Toddaline Broussonpapyrine) is a potent selective antagonist of PKC with an IC50 of 0 66 M Chelerythrine also inhibits the BclXL-Bak BH3 peptide binding with an IC50 of 1 5 M Chelerythrine shows antitumor antidiabetic and anti-inflammatory activity
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eMolecules LEUPEPTIN HEMISULFATE 10MG
5000190003 LEUPEPTIN HEMISULFATE 10MG
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5000344011 LM11A-31 DIHYDROCHL 10MM 1ML
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Apexbio Technology LLC NSC 74859 501919-59-1 200mg
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NSC 74859 (CAS 501919-59-1) also known as S3I-201 is a selective inhibitor of the signal transducer and activator of transcription 3 (Stat3) pathway S3I-201 disrupts Stat3 DNA-binding activity exhibiting an IC50 of 86 M in vitro with minimal inhibitory effects on Stat1 and Stat5 It also impedes the formation of Stat1-Stat3 and Stat1-Stat1 complexes with IC50 values of 160 M and 300 M respectively In NIH 3T3/v-Src fibroblasts S3I-201 reduces constitutive Stat3 activation and pTyr-705 Stat3 levels induces apoptosis at 30 100 M and downregulates cyclin D1 Bcl-xL and survivin expression This compound is widely utilized in research to interrogate Stat3 function in cellular transformation and oncogenic signaling pathways
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Apexbio Technology LLC RO4929097(Synonyms: RO-4929097, RO 4929097, Gamma-Secretase Inhibitor RO4929097, RO4929097 γ-secretase inhibitor), 200mg, CAS: 847925-91-1.
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RO4929097 (CAS 847925-91-1) is a potent selective small-molecule inhibitor of -secretase an essential protease in the Notch signaling pathway It inhibits -secretase with high specificity (IC50 4 nM EC50 5 nM) showing minimal inhibitory activity against closely related proteases and over 100-fold selectivity versus a broad spectrum of other proteases By preventing Notch receptor cleavage and subsequent signaling activation RO4929097 suppresses proliferation and tumorigenesis across various tumor models including melanoma breast colorectal pancreatic and lung cancers Clinical studies have assessed RO4929097 alone or combined with other anticancer agents for advanced solid tumors
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Apexbio Technology LLC ML385(Synonyms: ML-385, NRF2 inhibitor ML385, ML385 NRF2 inhibitor, ML385 inhibitor, NRF2-IN-1, NRF2-IN1), 200mg, CAS: 846557-71-9.
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ML385 (CAS 846557-71-9) is a selective inhibitor of the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) displaying an IC50 of 1 9 M NRF2 regulates cellular antioxidant responses detoxification pathways and multidrug transporters and its activation is frequently implicated in therapeutic resistance of non-small cell lung cancer (NSCLC) In A549 cells ML385 treatment reduces expression of NRF2-dependent genes dose- and time-dependently Additionally in NSCLC mouse models ML385 treatment diminished tumor growth and metastasis especially when combined with carboplatin underscoring its utility in cancer research and potential therapeutic exploration
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000439686 TL02-59 25MG
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eMolecules EMOLECULES INC
5000493044 4-CHLORO-3-NITROQUINOLINE 1G
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5000349188 S R S -AHPC-CO-C9-A 25MG
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